The cathedral floor, the museum and the Baptistery are step-free; the dome and bell tower are stairs only. Here is exactly what is reachable, and how to plan around the climbs.
Three of the six monuments are reachable without stairs. The cathedral's ground floor, the Opera del Duomo Museum and the Baptistery of San Giovanni all have step-free access, and the museum in particular is a modern, lift-served building that is comfortable to move through. If your visit is about the art and the interiors rather than the climbs, most of the Duomo is open to you.
The two climbs are the exceptions, and there is no way around it: neither has a lift.
The Santa Reparata crypt is reached by a staircase down from the cathedral floor, so it is likewise not step-free.
Some tours are described by their operators as wheelchair accessible for the cathedral and museum portions — look for that note on the individual tour's card, and contact the operator before booking to confirm the details for your needs.
If you are weighing up the dome or the bell tower with a knee, a hip or a nervous head for heights, it helps to know their shape. Both are continuous stone staircases with no lift and no exit once you have committed to going up. The dome's upper stretch curves with the shell and narrows to a single-file, one-way passage, and the final climb to the lantern is the steepest part; the bell tower is more regular but just as long at 414 steps. There are landings to pause on, but no seating on the way, and in summer the enclosed stairwells get warm. If any of that gives you pause, the museum and the cathedral floor offer the art and the atmosphere without the ascent.
If stairs are out, build your visit around the cathedral, the Baptistery and the museum, which together hold most of the complex's great art — Ghiberti's Gates of Paradise, Michelangelo's Bandini Pietà and Donatello's Magdalene are all in the step-free museum. For anything you are unsure about, the official Opera di Santa Maria del Fiore can confirm current access arrangements for your date.
To choose a suitable tour, compare the Florence Duomo tours and check each card's accessibility note, or see the full visiting guide for hours and entrances.
Several cathedral-and-museum tours are described by their operators as wheelchair accessible — compare them and confirm with the operator before you book.
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